Item
Publication
3-D nanocomposite scaffolds: Tissue engineering for bone reconstruction
- Title
- 3-D nanocomposite scaffolds: Tissue engineering for bone reconstruction
- Abstract
- A challenge to the orthopedic surgeons in veterinary and human fields is the treatment of delayed union, malunion and nonunion. Apart from renovation of arrangement and constant fixation, in many cases, adjunctive measures such as bone-grafting or the use of bone-graft substitutes, are of dominant significance. In general bone-graft materials comprise one or more components: an osteoconductive matrix, which acts as a scaffold to new bone growth; osteoinductive proteins, backing the mitogenesis of indistinguishable cells; and osteogenic cells, which can form bone in the proper environment. Our review focuses on the currently existing bone graft and graft substitutes for the novel therapeutic approaches in the clinical situation of orthopedic surgery. This review is based on an extensive literature search of different composite scaffolds developed as bone regenerative therapies. The settlement and drawbacks of different composite scaffold developed techniques, the properties of generally used ceramics and polymers, and the properties of presently investigated synthetic composite grafts. To follow, an exhaustive review of in vivo models is used to test composite scaffolds in segmental bone defects (SBDs) to serve as a guide to design suitable translational studies and to recognize the challenges that require to be overcome in scaffold design for successful transformation. This includes the formative of the anatomical position within the animals, selecting the accurate study period, and an overview of scaffold presentation evaluation
- Scientific Type
- اكاديمي
- Journal volume
- Vol. 36, No. 2
- Collaboration type
- مشترك
- Publish Date
- February 25, 2022
- Participated Universities (Publication)
-
Alnoor University
- Scopus status
- In Scopus
- Scopus index year
- 2 022
- Scopus quarter
- 2
- Scopus citation score
- 2.700000048
- Clarivate status
- Not In Clarivate
- Pub. Med. status
- Not In PubMed
- Author (Publication)
- زيد خضر محمود جبر
- Journal (Publication)
-
Iraqi Journal of Veterinary Sciences
- Publisher (Publication)
- Mosul University of Mosul, College of Veterinary Medicine
- ISSN
- 1607-3894
- Country (Publication)
-
Iraq
- Country type
- داخل العراق
- College (Publication)
-
College of Health and Medical Technologies
- Departement (Publication)
-
Department of Anesthesia Techniques
- Media
-
Academic Paper
Part of 3-D nanocomposite scaffolds: Tissue engineering for bone reconstruction