EFFECT OF INDUCING AND NON INDUCING ANTI-EPILEPTIC DRUGS ON LIVER ENZYMES IN EPILEPTIC PATIENTS
- Title
- EFFECT OF INDUCING AND NON INDUCING ANTI-EPILEPTIC DRUGS ON LIVER ENZYMES IN EPILEPTIC PATIENTS
- Abstract
-
Carbamazepine and levetiracetam are one of the most common anti-epileptic drugs used in clinical practice.
This study was conducted to assess the effect of carbamazepine and levetiracetam on serum liver enzymes in
67 epileptic patients. The patients were separated into 2 groups. Group I, 31 patients treated with
carbamazepine and group II, 36 patients treated with levetiracetam. Serum liver enzymes AST, ALT and ALP
were determined. No patients developed clinical symptoms of liver disease. A significant low elevation of the
AST, ALT, ALP were noted in the carbamazepine group and a non significant difference were noted in the
levetiracetam group. In conclusion the study showed a lowered proportion of liver enzyme abnormalities and
there were no any clinical abnormalities. There is no proven value of routine liver enzyme measurement in
asymptomatic patients. - Scientific Type
- اكاديمي
- Journal volume
- vol.32,No.3
- Collaboration type
- مشترك
- Publish Date
- December 1, 2021
- Scopus status
- Not in Scopus
- Clarivate status
- Not In Clarivate
- Pub. Med. status
- Not In PubMed
- Author (Publication)
-
عصام حمو محمود شهاب
- Journal (Publication)
- Turkish Journal of Physiotherapy and Rehabilitation
- Publisher (Publication)
- Turkish Physiotherapy Association
- ISSN
- 2651-4451
- Country (Publication)
-
Turkey
- Country type
- عالمية
- College (Publication)
-
College of Pharmacy
- Departement (Publication)
-
Department of Pharmacy
- Media
-
Academic Paper
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