Enhancing Adverse Drug Reaction Reporting in Pediatrics and Its Impact on Public Health: A Systematic Review and Meta-Analyses
- Title
- Enhancing Adverse Drug Reaction Reporting in Pediatrics and Its Impact on Public Health: A Systematic Review and Meta-Analyses
- Abstract
-
Adverse drug reactions (ADRs) pose a significant public health concern, especially in pediatrics. ADRs are defined as any undesirable or unintended response to a drug, ranging from mild and self-limited to severe and life-threatening. It is estimated that ADRs affect up to 25% of hospitalized children, making them a leading cause of morbidity and mortality in this population. This study aimed to comprehensively review available evidence regarding the effectiveness of different interventions in enhancing ADR reporting in pediatric populations. In October 2023, we conducted a search on the electronic database Medline PubMed without imposing limitations on the publication date or geographic area, excluding all secondary and tertiary literature. Data were extracted from identified studies using a structured data extraction form in Microsoft Office Excel® 2016. The systematic search yielded a total of 108 records. After removing seven duplicate records, 101 distinct records underwent title and abstract screening. Six were excluded due to language restrictions or irrelevance to the research topic. Subsequent full-text assessment for eligibility resulted in the exclusion of an additional 79 records, primarily due to the absence of intervention in the study design. Ultimately, 16 studies were deemed suitable for quantitative synthesis. This systematic review and meta-analysis revealed that interventions aimed at improving adverse drug reaction detection and reporting increased identification compared to standard practice in children. However, concerns about significant issues related to bias and heterogeneity threaten the reliability of our results.
- Scientific Type
- تطبيقي
- Journal volume
- vol.7,No.se iss
- Collaboration type
- مشترك
- Publish Date
- November 25, 2023
- Participated Universities (Publication)
-
Alnoor University
- Scopus status
- In Scopus
- Scopus index year
- 2 024
- Scopus quarter
- 4
- Scopus citation score
- 0.899999976
- Clarivate status
- Not In Clarivate
- Pub. Med. status
- Not In PubMed
- Author (Publication)
-
عمر قتيبة بدر الدين محمود
- Journal (Publication)
- Journal of Wildlife and Biodiversity
- Publisher (Publication)
- Science Press
- ISSN
- 2588-3526
- Country (Publication)
-
Iran
- Country type
- عالمية
- College (Publication)
-
College of Pharmacy
- Departement (Publication)
-
Department of Pharmacy
- Media
-
Academic Paper
