Alterations in the levels of plasma amino acids polycystic ovary syndrome
- Title
- Alterations in the levels of plasma amino acids polycystic ovary syndrome
- Abstract
-
Background & objectives: Polycysticovary syndrome (PCOS) is a heterogenous endocrinopathy commonly diagnosed in reproductive age women, predisposing to the development of metabolic disturbances. However, the mechanisms underlying the connection between PCOS, and metabolic disorders are still not well understood. The aim of the study was to investigate amino acid (AA) profile in women with PCOS and to assess its relation with metabolic disturbances. Methods: This study included sixty-five women with PCOS along with a similar number of age-matched normal controls in this study. Levels of 14 amino acids were determined using reverse phase high-performance liquid chromatography. Results The levels of methionine, cysteine, isoleucine, phenylalanine, valine, tyrosine, proline, glycine, lysine and histidine were significantly lower (p < 0.001) than in the control group. It was also observed that the levels of arginine and alanine were significantly (P < 0.001) higher in the cases compared to the control group. Interpretation & conclusions: Our findings showed significant derangement in the levels of plasma amino acids in women with PCOS which might be due to the oxidative and metabolic stress associated with it. Further studies need to be done to confirm the findings.
- Scientific Type
- تطبيقي
- Journal volume
- vol.23,No.2
- Collaboration type
- منفرد
- Publish Date
- January 25, 2023
- Participated Universities (Publication)
-
Alnoor University
- Scopus status
- Not in Scopus
- Clarivate status
- Not In Clarivate
- Pub. Med. status
- In PubMed
- Author (Publication)
- امل موفق صالح ياسين
- Journal (Publication)
- HIV Nursing
- Publisher (Publication)
- Mediscript Ltd.
- ISSN
- 1474-7359
- Country (Publication)
-
United kingdom
- Country type
- عالمية
- College (Publication)
-
College of Health and Medical Technologies
- Departement (Publication)
-
Department of Optics Techniques
- Media
-
Academic Paper
Part of Alterations in the levels of plasma amino acids polycystic ovary syndrome