The Antifungal Efficacy of Heat-Cured Acrylic-Based Soft Denture Liners Infused with Magnesium Oxide Nanoparticles

Title

The Antifungal Efficacy of Heat-Cured Acrylic-Based Soft Denture Liners Infused with Magnesium Oxide Nanoparticles

Abstract

Candida albicans (C. albicans) colonization of denture soft lining materials can cause clinical issues and material deterioration. Given their antibacterial qualities, of magnesium oxide nanoparticles (MgONPs) have generated interest for usage in biomedical applications. This research intended to determine how adding MgONPs to a soft heat-cured acrylic resin denture liner influenced its water sorption, solubility, antifungal activity, and color modification. Moreover, assessing the quantity of MgO released. Soft denture liner was infused with 0.1%, 0.2%, and 0.3% of MgONPs. A total of 200 specimens have been prepped and separated into four groups based on the test that will be run. The antifungal effects of a composite material comprised of a soft liner and MgONPs were determined using a viable count of C. albicans in combination with a disk-diffusion method (DDM). Using atomic absorption spectroscopy (AAS), researchers could determine the amount of MgO released by synthetic saliva. The findings of the measurements of the color change, shear bond strength, solubility, and water sorption have been statistically examined. When compared to the control group, all experimental groups displayed a highly significant decline in C. albicans colony forming units. No inhibition zone surrounded any test specimens utilized in any of the tested groups. The incorporation of MgONPs aids in producing a soft denture liner with antifungal properties. In addition to decreasing water sorption, this addition also raised the material’s opacity while having no effect on the shear bond strength.

Scientific Type

اكاديمي

Link

https://jns.kashanu.ac.ir/article_112819.html

Journal volume

vol.12,No.3

Collaboration type

مشترك

Publish Date

July 1, 2022

Participated Universities (Publication)

Alnoor University

Al Nisour University College

Hilla University College

Al Mustaqbal University College

AL Farahidi University

Mazaya University College

Scopus status

In Scopus

Scopus index year

2 022

Scopus quarter

3

Scopus citation score

2

Clarivate status

In Clarivate

Clarivate index year

2 022

Clarivate impafact

0.261000007

Pub. Med. status

Not In PubMed

Author (Publication)

زينة سالم عوفي محمد

Journal (Publication)

Journal of Nanostructures

Publisher (Publication)

University of Kashan

ISSN

2251-7871

Country (Publication)

Iran

Country type

عالمية

College (Publication)

College of Health and Medical Technologies

Departement (Publication)

Department of Dental Prosthetics Techniques