Impact of low carbohydrate diet on patients with type 1 Diabetes · Alnoor Digital Repository

Title: Impact of low carbohydrate diet on patients with type 1 Diabetes
Abstract: Introduction: Achieving glycemic control in subjects with type 1 diabetes presents a significant challenge to the patient and the healthcare providers. The recommendations for dietary carbohydrates varied over the years from severe restriction to no restriction. We aim to study the impact of low carbohydrate diet on subjects with type 1 diabetes.

Subjects and Methods: we conducted a cross over clinical trial in which 46 uncontrolled (HbA1c ≥7%), subjects with type 1 diabetes on a standard carbohydrate diet, were placed on low carbohydrate diet (<26% of daily caloric intake). Patients attending Ain Shams University hospitals outpatient diabetes clinics were invited to participate. Participants were provided with education sessions to achieve and maintain low carbohydrate diet. They visited the clinic at baseline, 3 and 6 months.

Results: low carbohydrate diet resulted in significant improvement (p<0.001) in the following parameters using repeated measure analysis of variance: HbA1c (9.2 to 6.6%), weight (82.7kg to 76.7kg), BMI (29.70 to 27.56 Kg/m2), percent body fat (36.7 to 30.2%), skeletal muscle mass (53.8 to 55.9kg), total daily dose of insulin (72 to 54 IU) total cholesterol (199 to 169 mg/dL), LDL (119 to 101mg/dL) triglycerides (182 to 113 mg/dL), ALT (23 to 20IU/L), AST (14 to 12 IU/L), UAC ratio ( 15.7 to 14.0mg/g) and decreased incidence of hypoglycemic and hyperglycemic events (4.4 to 1.1 and 20.8 to 4.0 events/week respectively).

Conclusion: low carbohydrate diet demonstrated efficacy in terms of glycemic control and attainment of glycemic targets with good safety profile in terms of lower rates of hypoglycemic events.
Scientific Type: غير معروف
Link: https://www.e3s-conferences.org/articles/e3sconf/abs/2023/28/e3sconf_icmed-icmpc2023_01132/e3sconf_icmed-icmpc2023_01132.html
Journal volume: vol.391,2023
Collaboration type: منفرد
Publish Date: June 5, 2023
Participated Universities (Publication): Alnoor University
Scopus status: In Scopus
Scopus index year: 2 023
Scopus quarter: 3
Scopus citation score: 0.899999976
Clarivate status: Not In Clarivate
Pub. Med. status: Not In PubMed
Author (Publication): بشار شاكر محمود داؤد
Journal (Publication): E3S Web of Conferences
Publisher (Publication): Les Ulis EDP Sciences 2013-
ISSN: 2267-1242
Country (Publication): France
Country type: عالمية
College (Publication): College of Health and Medical Technologies
Departement (Publication): Department of Anesthesia Techniques

Media: Academic Paper