Determination of Oxidative Stress Markers in Women with Polycystic Ovarian Syndrome
- Title
- Determination of Oxidative Stress Markers in Women with Polycystic Ovarian Syndrome
- Abstract
- Polycystic ovarian syndrome (PCOS) is a condition that increases the risk of metabolic diseases, such as insulin resistance, diabetes mellitus, and obesity, among others. Oxidative stress is a state of elevated oxidants and reduced antioxidants, which can be detrimental to the body. Reduced glutathione (GSH) is an important material with antioxidant properties. This study aimed to investigate the status of oxidative stress in PCOS women by measuring total oxidant status (TOS) and GSH in their serum, and explore the possibility of using oxidative stress biomarkers in the diagnosis of the disease. The study included 60 women with PCOS and 30 women without PCOS as controls. PCOS women had significantly higher values of body mass index, testosterone, and TOS, while GSH levels were significantly reduced. There was also a significant negative correlation between TOS and GSH levels in PCOS women. These findings indicate that PCOS women exhibit systemic oxidative stress, and suggest the use of anti-oxidative drugs to manage the health consequences of PCOS. The study demonstrates the excellent sensitivity of TOS and GSH as prognostic biomarkers for PCOS.
- Scientific Type
- غير معروف
- Journal volume
- Volume 391, 2023
- Collaboration type
- منفرد
- Publish Date
- June 5, 2023
- Participated Universities (Publication)
-
Alnoor University
- Scopus status
- In Scopus
- Scopus index year
- 2 023
- Scopus quarter
- 3
- Scopus citation score
- 0.899999976
- Clarivate status
- Not In Clarivate
- Pub. Med. status
- Not In PubMed
- Author (Publication)
- امل موفق صالح ياسين
- Journal (Publication)
- E3S Web of Conferences
- Publisher (Publication)
- Les Ulis EDP Sciences 2013-
- ISSN
- 2267-1242
- Country (Publication)
-
France
- Country type
- عالمية
- College (Publication)
-
College of Health and Medical Technologies
- Departement (Publication)
-
Department of Optics Techniques
- Media
-
Academic Paper
Part of Determination of Oxidative Stress Markers in Women with Polycystic Ovarian Syndrome