The role of Interleukin-21 (IL-21) in allergic disorders: Biological insights and regulatory mechanisms
- Title
- The role of Interleukin-21 (IL-21) in allergic disorders: Biological insights and regulatory mechanisms
- Abstract
- In recent decades, allergic diseases subsequent from an IgE-mediated response to specific allergens have become a progressively public chronic disease worldwide. They have shaped an important medical and socio-economic burden. A significant proportion of allergic disorders are branded via a form 2 immune response relating Th2 cells, type 2 natural lymphoid cells, mast cells and eosinophils. Interleukin-21 (IL-21) is a participant of the type-I cytokine family manufactured through numerous subsets of stimulated CD4+ T cells and uses controlling properties on a diversity of immune cells. Increasingly, experimental sign suggests a character for IL-21 in the pathogenesis of numerous allergic disorders. The purpose of this review is to discuss the biological properties of IL-21 and to summaries current developments in its role in the regulation of allergic disorders.
- Scientific Type
- غير معروف
- Journal volume
- vol.134
- Collaboration type
- مشترك
- Publish Date
- May 8, 2024
- Participated Universities (Publication)
-
Alnoor University
- Scopus status
- In Scopus
- Scopus index year
- 2 024
- Scopus quarter
- 1
- Scopus citation score
- 8.399999619
- Clarivate status
- In Clarivate
- Clarivate index year
- 2 024
- Clarivate impafact
- 5.699999809
- Pub. Med. status
- In PubMed
- Author (Publication)
- بشار عبدالله سعيد ذنون
- Journal (Publication)
- International Immunopharmacology
- Publisher (Publication)
-
Elsevier
- ISSN
- 1567-5769
- Country (Publication)
-
Netherlands
- Country type
- عالمية
- College (Publication)
-
College of Health and Medical Technologies
- Departement (Publication)
-
Department of Medical laboratories techniques