The role of kinesin superfamily proteins in hepatocellular carcinoma · Alnoor Digital Repository

Title: The role of kinesin superfamily proteins in hepatocellular carcinoma
Abstract: The most prevalent form of primary liver cancer, hepatocellular carcinoma (HCC) poses a significant global health challenge due to its limited therapeutic options. Researchers are currently focused on the complex molecular landscape that governs the initiation and progression of HCC in order to identify new avenues for diagnosis, prognosis, and treatment. In the context of HCC, the Kinesin Superfamily Proteins (KIFs) have become critical regulators of cellular processes, prompting a growing interest in their function among the diverse array of molecular actors implicated in cancer. The KIFs, a family of microtubule-based molecular motors, are renowned for their essential roles in the dynamics of mitotic spindles and intracellular transport. Beyond their well-established functions in normal cellular physiology, emerging evidence indicates that dysregulation of KIFs significantly contributes to the pathogenesis of HCC. Novel therapeutic targets and diagnostic markers are revealed through the unique opportunity to comprehend the complex interplay between KIFs and the molecular events that drive HCC.
Scientific Type: غير معروف
Link: https://link.springer.com/article/10.1007/s12032-024-02497-0
Journal volume: Volume 41, Issue 11
Collaboration type: مشترك
Publish Date: October 14, 2024
Participated Universities (Publication): Alnoor University
Scopus status: In Scopus
Scopus index year: 2 024
Scopus quarter: 2
Scopus citation score: 4.599999905
Clarivate status: Not In Clarivate
Pub. Med. status: In PubMed
Author (Publication): زهراء صباح غانم سعدالله
Journal (Publication): Medical Oncology
Publisher (Publication): Springer Nature
ISSN: 1357-0560
Country (Publication): United kingdom
Country type: عالمية
College (Publication): College of Pharmacy
Departement (Publication): Department of Pharmacy