The potential use of bacteriophages as antibacterial agents in dental infection
- Title
- The potential use of bacteriophages as antibacterial agents in dental infection
- Abstract
- Dental infections, such as apical Periodontitis, periodontitis, and peri-implantitis (PI), are closely associated with specific bacterial species, including Streptococcus mutans (S. mutans), Porphyromonas gingivalis (P. gingivalis), and Fusobacterium nucleatum (F. nucleatum), among others. Antibiotics are extensively utilized for prophylactic and therapeutic purposes in the treatment of dental infections and other dental-related issues. Unfortunately, the rapid emergence of antimicrobial resistance has accompanied the increased use of antibiotics in recent years. Specific bacterial pathogens have reached a critical stage of antibiotic resistance, characterized by the proliferation of pan-resistant strains and the scarcity of viable therapeutic alternatives. Therapeutic use of particular bacteriophage (phage) particles that target bacterial pathogens is one potential alternative to antibiotics that are now being seriously considered for treating bacterial illnesses. A kind of virus known as a phage is capable of infecting and eliminating bacteria. Because they can’t infect cells in plants and animals, phages might be a harmless substitute for antibiotics. To control oral disorders including periodontitis and dental caries, several research have been conducted in this area to study and identify phages from human saliva and dental plaque. The capacity of these agents to disturb biofilms expands their effectiveness against dental plaque biofilms and oral pathogens in cases of periodontitis, PI, and apical periodontitis. This review summarizes the current antibacterial properties of phages used to treat a variety of dental infections, such as periodontitis, peri-implantitis, infected dentin, and apical periodontitis.
- Scientific Type
- غير معروف
- Journal volume
- Volume 21, Issue 1
- Collaboration type
- مشترك
- Publish Date
- October 18, 2024
- Participated Universities (Publication)
-
Alnoor University
- Scopus status
- In Scopus
- Scopus index year
- 2 024
- Scopus quarter
- 1
- Scopus citation score
- 6.099999905
- Clarivate status
- In Clarivate
- Pub. Med. status
- In PubMed
- Author (Publication)
- علا سمير سالم عبدالجبار
- Journal (Publication)
- Virology journal
- Publisher (Publication)
-
Springer Nature
- ISSN
- 1743-422X
- Country (Publication)
-
United kingdom
- Country type
- عالمية
- College (Publication)
-
College of Dentistry
- Departement (Publication)
-
Department of Dentistry
- Media
-
Academic paper
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